Through the use of advanced imaging techniques, including super-resolution live imaging, two-photon imaging, MALDI MS imaging and other interdisciplinary imaging tools, our team is committed to exploring dynamic changes at the cellular level and intact organisms, metabolism during development and disease, and functional interactions between nanomaterials and biological system.
X. Chen, A. Momin, S. Wanggou, X. Wang, H.-K. Min, W. Dou, Z. Gong, J. Chan, W. Dong, J. J. Fan, Y. Xiong, K. Talipova, H. Zhao, Y. X. Chen, K. Veerasammy, A. Fekete, S. A. Kumar, H. Liu, Q. Yang, J. E. Son, et al. Mechanosensitive Brain Tumor Cells Construct Blood-Tumor Barrier to Mask Chemosensitivity. Neuron, 2022. DOI: https://doi.org/10.1016/j.neuron.2022.10.007.
A. Jain, S. Kassem, R.S. Fisher, B. Wang, T.-D. Li, T. Wang, Y. He, S. Elbaum-Garfinkle, and R.V. Ulijn, Connected Peptide Modules Enable Controlled Co-Existence of Self-Assembled Fibers Inside Liquid Condensates, J. Am. Chem. Soc., 2022, 144 (33), 15002–15007. DOI: https://doi.org/10.1021/jacs.2c05897.
G. A. Soliman, R. R. Abzalimov, Y. He. MTORC1 and MTORC2 Complexes Regulate the Untargeted Metabolomics and Amino Acid Metabolites Profile through Mitochondrial Bioenergetic Functions in Pancreatic Beta Cells. Nutrients, 2022, 14 (15), 3022. DOI: https://doi.org/10.3390/nu14153022.
Y. X. Chen, K. Veerasammy, J. Yin, T. Choetso, T. Zhong, M. A. Choudhury, C. Weng, E. Xu, M. A. Hein, R. Abzalimov, Y. He. Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging. JoVE (Journal of Visualized Experiments), 2022, No. 185, e63930. DOI: https://doi.org/10.3791/63930.
R.H. Huang, N. Nayeem, Y. He, J. Morales, D. Graham, R. Klajn, M. Contel, S. O’Brien, and R.V. Ulijn. Self‐Complementary Zwitterionic Peptides Direct Nanoparticle Assembly and Enable Enzymatic Selection of Endocytic Pathways, Adv. Mater., 2021, 2104962, DOI: https://doi.org/10.1002/adma.202104962.
- December 16, 2022
Congratulations to our lab member, Amos, on being accepted into Johns Hopkins University Biomedical Engineering! Way to go!
- December 9, 2022
Our lab member, Muniyat, won the ASRC’s “best representing NYC” snow globe competition! So creative!
- November 18, 2022
We welcome students from the Macaulay Honors Seminar 3 class to visit the ASRC. Thank you to our tour hosts: Drs. Ricardo Toledo-Crow, Samantha Roberts, Tong Wang, Duke Shereen, Tai-De Li, Jia Liu, & Rinat Abzalimov!
- November 3, 2022
Congratulations to Xi Huang’s group from SickKids & U Toronto for their ground breaking work Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity ! Glad that our MALDI imaging core and Live Imaging Core be part of it. Good job, Kelly and Yuki! And many thanks to those helped tremendously on this project: Jorge Morales, Tong Wang, Sheng Zhang, Zhi-Lun Liu, Avani Butala, and Elvina Abzalimov! Read more here.
- August 10, 2022
Congratulations to the Ulijn and Elbaum-Garfinkle labs on our collaborative study of self-assembling peptides being published in JACS! Very exciting interdisciplinary work!
- July 22, 2022
Our collaborative study with Ghada Soliman on regulatory mechanisms in pancreatic beta cells was published in Nutrients. Great work, everyone!
- July 14, 2022
We are happy to share that our methodology paper on MALDI sample preparation for Drosophila head lipid analysis has been published in JoVe!
- June 24, 2022
We held our first Advanced Imaging Workshop for high school and undergraduate students. Good work Allison, Amos, Ethan, Georgia, Salma, Shadman, and Tiffany!
- June 3, 2022
Congratulations to Tenzin on graduating with her Bachelors from City College, and to Yuki for completing her Masters of Public Health (and receiving the Dean’s Merit Award for Excellence)! We are so proud of you both!
- May 6, 2022
Muni has been awarded the Velay Women’s Scholars Research Fellowship! Many congratulations!