Through the use of advanced imaging techniques, including super-resolution live imaging, two-photon imaging, MALDI MS imaging and other interdisciplinary imaging tools, our team is committed to exploring dynamic changes at the cellular level and intact organisms, metabolism during development and disease, and functional interactions between nanomaterials and biological system.
Recent Publications
- W. Dong, A. Fekete, X. Chen, H. Liu, G. L. Beilhartz, X. Chen, S. Bahrampour, Y. Xiong, Q. Yang, H. Zhao, T. Kong, M. S. Morioka, G. Jung, J.-E. Kim, D. Schramek, P. B. Dirks, Y. Song, T.-H. Kim, Y. He, S. Wanggou, et al. A Designer Peptide against the EAG2–Kvβ2 Potassium Channel Targets the Interaction of Cancer Cells and Neurons to Treat Glioblastoma. Nat Cancer, 2023. DOI: https://doi.org/10.1038/s43018-023-00626-8.
- M. Pruvost, J. Patzig, C. Yattah, I. Selcen, M. Hernandez, H.-J. Park, S. Moyon, S. Liu, M. S. Morioka, L. Shopland, O. Al-Dalahmah, J. Bendl, J. F. Fullard, P. Roussos, J. Goldman, Y. He, J. L. Dupree, P. Casaccia. The Stability of the Myelinating Oligodendrocyte Transcriptome Is Regulated by the Nuclear Lamina. Cell Reports, 2023, 42 (8), 112848. DOI: https://doi.org/10.1016/j.celrep.2023.112848.
X. Chen, A. Momin, S. Wanggou, X. Wang, H.-K. Min, W. Dou, Z. Gong, J. Chan, W. Dong, J. J. Fan, Y. Xiong, K. Talipova, H. Zhao, Y. X. Chen, K. Veerasammy, A. Fekete, S. A. Kumar, H. Liu, Q. Yang, J. E. Son, et al. Mechanosensitive Brain Tumor Cells Construct Blood-Tumor Barrier to Mask Chemosensitivity. Neuron, 2022. DOI: https://doi.org/10.1016/j.neuron.2022.10.007.
A. Jain, S. Kassem, R.S. Fisher, B. Wang, T.-D. Li, T. Wang, Y. He, S. Elbaum-Garfinkle, and R.V. Ulijn, Connected Peptide Modules Enable Controlled Co-Existence of Self-Assembled Fibers Inside Liquid Condensates, J. Am. Chem. Soc., 2022, 144 (33), 15002–15007. DOI: https://doi.org/10.1021/jacs.2c05897.
G. A. Soliman, R. R. Abzalimov, Y. He. MTORC1 and MTORC2 Complexes Regulate the Untargeted Metabolomics and Amino Acid Metabolites Profile through Mitochondrial Bioenergetic Functions in Pancreatic Beta Cells. Nutrients, 2022, 14 (15), 3022. DOI: https://doi.org/10.3390/nu14153022.
What's New
January 10, 2024
Big congratulations to Steven Xiang for being named as one of the national 300 scholars in the Regeneron Science Talent Search 2024, the nation’s oldest and most prestigious science and math competition for high school seniors!! Thanks to the mentorship of Lele, Malia and Areej!
January 2, 2024 Welcome Tiffany Zhong joinin back to the lab this winter as a research intern from Princeton Neuroscience program!
October 25, 2023 Congratulations to Xi Huang’s Lab on their recent publication in Nature Cancer about a designer peptide that targets neuron-associated glioblastoma cells! Their work was featured as a Nature Cancer Cover Story. Many thanks to Dr. Rinat Abzalimov, Dr. Tai-De Li and Malia Morioka for their help on this project! Read the news here: The never-abating excitement for targeted therapies | Nature Cancer & Targeting network circuitry in glioma | Nature Cancer
September 13, 2023 We are happy to announce that Lele Xu is joining our lab as Dr. He’s first PhD student! Welcome Lele!
August 10, 2023 Congratulations to Malia and Olivia on completing the Velay Fellowship and presenting their hard work at the Velay 2023 Symposium!
August 9, 2023 Congratulations to Mathilde Pruvost and the Casaccia lab on their recent publication in Cell Reports about their exciting finding of LMNA/C being essential for the stability of myelinating oligodendrocytes! Thanks to Shibo and Malia for their help on the project!
July 17, 2023 We are happy to announce Areej Niaz as our new research assistant for the MALDI Imaging Core. Welcome Areej!
June 26, 2023 We are excited to welcome Lele Xu, a first year PhD student at the CUNY Graduate Center, on her rotation in our lab. Welcome Lele!
June 15, 2023 We are excited to welcome Steven Xiang to our lab as a high school research intern. Welcome Steven!
June 12, 2023 We are excited to host the Advanced Bio-Imaging Camp, which is a week-long summer program for high school students and undergraduates that offers an opportunity for immersion in cutting-edge imaging technologies, neuroscience research, and interdisciplinary research. Hosted by Live Imaging Core and jointly by MRI Suite, MALDI imaging Core, Surface Science Core, and Nano Imaging Suite, the 2023 Imaging Camp (June 12-16) features lectures, seminars and laboratory hands-on. Participants include students from NY, NJ, CT, MA, MD, NC, SC. We are grateful for our lecturers and guest speakers from CUNY, Columbia, Rockefeller, Princeton, JHU, SUNY, UMass, NIH, Duke, Novant Health Medical Center, Yale and Shanghai Institute of Immunology.
May 10, 2023 CUNY Medical School student, Olivia Yeroushalmi, is joining the lab this summer as a Velay Scholar. Welcome Olivia!
May 10, 2023 Our lab member, Malia, has been awarded the Velay Women’s Scholars Research Fellowship! Congratulations!
March 6, 2023 We are happy to announce Shibo Liu as our new research assistant for the MALDI Imaging Core. Welcome Shibo!
- March 31, 2023
Congratulations to Tiffany for being accepted into NIH Sumer Internship Program! Two years in a row, good job!
- March 10, 2023
Cory is awarded the Harold Scheraga Honorary Distinction, congratulations!
- January 24, 2023
Thanks ASRC for awarding us the ASRC Core Facilities Personnel Grant (CFGP)! MALDI imaging core will get in gear soon!
- December 20, 2022
Cory was awarded the Benjamin A. Gilman International Scholarship Award! Congratulations!
- December 16, 2022
Congratulations to our lab member, Amos, on being accepted into Johns Hopkins University Biomedical Engineering! Way to go!
- December 9, 2022
Our lab member, Muniyat, won the ASRC’s “best representing NYC” snow globe competition! So creative!
- November 18, 2022
We welcome students from the Macaulay Honors Seminar 3 class to visit the ASRC. Thank you to our tour hosts: Drs. Ricardo Toledo-Crow, Samantha Roberts, Tong Wang, Duke Shereen, Tai-De Li, Jia Liu, & Rinat Abzalimov!
- November 3, 2022
Congratulations to Xi Huang’s group from SickKids & U Toronto for their ground breaking work Mechanosensitive brain tumor cells construct blood-tumor barrier to mask chemosensitivity ! Glad that our MALDI imaging core and Live Imaging Core be part of it. Good job, Kelly and Yuki! And many thanks to those helped tremendously on this project: Jorge Morales, Tong Wang, Sheng Zhang, Zhi-Lun Liu, Avani Butala, and Elvina Abzalimov! Read more here.
- August 10, 2022
Congratulations to the Ulijn and Elbaum-Garfinkle labs on our collaborative study of self-assembling peptides being published in JACS! Very exciting interdisciplinary work!
- July 22, 2022
Our collaborative study with Ghada Soliman on regulatory mechanisms in pancreatic beta cells was published in Nutrients. Great work, everyone!